{"product_id":"enantioselective-electrochemical-ch-acti","title":"Enantioselective Electrochemical Ch Acti","description":"\u003cp\u003eEnantioselective metallaelectro-catalyzed C-H activation represents an innovative strategy for enabling the transition of organic synthesis to a more resource-economic mode of operation. It circumvents substrate prefunctionalization by directly exploiting otherwise inert C-H bonds to construct complex three-dimensional scaffolds from simple molecular building blocks. Furthermore, the mild electrocatalytic conditions evade chemical oxidants, while producing molecular hydrogen as the sole by-product, enabling the connection of organic synthesis to a possible future decentralized green hydrogen economy.\u003cbr\u003eStill, disclosed methodologies predominantly rely on noble metal catalysts. Examples using earth-abundant 3d transition metals remain scarce despite the substantially improved ecological and economic implications and diminished toxicity. This work addresses this shortcoming by investigating the first enantioselective nickelaelectro-catalyzed C-H activation and various cobaltaelectro-catalyzed conversions. On this occasion, the synthetic versatility is examined and various mechanistic experiments are presented for fostering future developments.\u003c\/p\u003e","brand":"MediaPlace","offers":[{"title":"Default Title","offer_id":57195048993150,"sku":"NW9783658471095","price":74.59,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1379\/1261\/files\/9783658471095.jpg?v=1778538419","url":"https:\/\/mediaplace.com\/products\/enantioselective-electrochemical-ch-acti","provider":"MediaPlace","version":"1.0","type":"link"}