{"product_id":"targeting-rna-with-small-molecules","title":"Targeting Rna With Small Molecules","description":"\u003cp\u003e\u003cb\u003eDiscover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eExisting paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eRNA as a Drug Target: The Next Frontier for Medicinal Chemistry \u003c\/i\u003eoffers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eRNA as a Drug Target \u003c\/i\u003ereaders will also find:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eA complete “toolbox” for working with RNA, from structure determination to screening and lead generation techniques\u003c\/li\u003e \u003cli\u003eA wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more\u003c\/li\u003e \u003cli\u003eAuthoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eRNA as a Drug Target\u003c\/i\u003e provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.\u003c\/p\u003e","brand":"MediaPlace","offers":[{"title":"Default Title","offer_id":57310242996606,"sku":"NW9783527351008","price":88.98,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1379\/1261\/files\/9783527351008.jpg?v=1778576895","url":"https:\/\/mediaplace.com\/products\/targeting-rna-with-small-molecules","provider":"MediaPlace","version":"1.0","type":"link"}